Prince William praises the efforts of Oxford team developing COVID-19 vaccine

Grant Boone
June 27, 2020

Other trials led by the group are taking place in South Africa and Brazil, with the hope an effective vaccine could be rolled out this year.

The confirmed Coronavirus cases in the World near Ten Million.

Imperial College London's vaccine candidate is being developed and trialled thanks to more than £41 million in funding from the United Kingdom government and a further £5 million in philanthropic donations. Including SII, seven institutions are partnering with Oxford University to manufacture the vaccine. Several traditional vaccines are based on a weakened or modified form of virus or parts of it.

In the fourth week of May, the Oxford Vaccine Group had begun recruiting participants for Phase 2-3 trials.

Given to a person with a healthy immune system, the Imperial vaccine has proven to be safe and productive during its pre-clinical tests.

Stephen Griffin, an associate professor at Leeds University who was not directly involved in this work, said it was "an encouraging advance" and showed that "a so-called "prime-boost" strategy gives rise to far better responses" than a single dose. Explaining why the results of the trial on monkeys is not discouraging, Mr. Jadhav said: "The monkeys were exposed to very high concentration of the virus, and only a single dose of the vaccine was used for immunising the monkeys".

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He was a part of 6 different Stanley Cup winning teams, five with the Edmonton Oilers and one with the Rangers. Wilson was the seventh overall selection by Chicago in the 1977, and would play 14 seasons with the Blackhawks.

"We have reached a significant milestone in this ground-breaking study with the first dose of a self-amplifying RNA vaccine delivered safely", said Dr Katrina Pollock, from Imperial's Department of Infectious Disease and Chief Investigator of the study.

The ChAdOx1 nCoV-19 vaccine, also known as AZD1222, will be given to 10,260 adults and children in the next stage in the UK.

During the fast-spreading initial outbreak of the coronavirus in Wuhan, China, the R0 was estimated at around 2.5, according to a World Health Organization analysis.

Zydus Cadila in Ahmedabad and India Immunologicals in Hyderabad are also working together to develop Covid-19 vaccines.

Imperial's vaccine is the first one to trial saRNA against COVID-19, but other RNA-based vaccines are also in clinical trials for coronavirus, namely Moderna's mRNA-1273 - already in late-stage testing - and BioNTech/Fosun Pharma/Pfizer's BNT161.

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